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Results for "

Rho-associated protein kinase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ROCK (2)
By Research Areas:	Cancer (1) Cardiovascular Disease (1)

2

Inhibitors & Agonists

2

Recombinant Proteins

Targets Recommended: ROCK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

GSK180736A 4 Publications Verification	ROCK	Cardiovascular Disease
GSK180736A is potent Rho-associated coiled-coil kinase 1 (ROCK1) inhibitor with an IC₅₀ of 100 nM. GSK180736A is also a selective and ATP-competitive *G protein-coupled receptor kinase* 2 (GRK2) inhibitor with an IC₅₀** of 0.77 μM.

WF-536	ROCK	Cancer
WF-536 is an orally active inhibitor of Rho-associated coiled-coil-containing protein kinase (ROCK). WF-536 has tumor anti-metastatic activity. WF-536 can be used for the research of cancer .

Species:	Human (2)
Tag:	His (1) Tag Free (1)
Source:	Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

	ROCK1 Protein, Human (Sf9) ROCK1; Rho-associated protein kinase 1; Renal carcinoma antigen NY-REN-35; Rho-associated; coiled-coil-containing protein kinase 1; Rho-associated; coiled-coil-containing protein kinase I; ROCK-I; p160 ROCK-1; p160ROCK	Human	Sf9 insect cells
	The ROCK1 protein is a key kinase that regulates the actin cytoskeleton, cell polarity, smooth muscle contraction, and multiple cellular functions. It controls stress fibers, focal adhesion formation, neurite retraction, and cell motility by phosphorylating substrates such as DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1, and PPP1R12A. ROCK1 Protein, Human (Sf9) is the recombinant human-derived ROCK1 protein, expressed by Sf9 insect cells , with tag free. The total length of ROCK1 Protein, Human (Sf9) is 410 a.a., .

	ROCK1 Protein, Human (Sf9, His) ROCK1; Rho-associated protein kinase 1; Renal carcinoma antigen NY-REN-35; Rho-associated; coiled-coil-containing protein kinase 1; Rho-associated; coiled-coil-containing protein kinase I; ROCK-I; p160 ROCK-1; p160ROCK	Human	Sf9 insect cells
	The ROCK1 protein is a key kinase that regulates the actin cytoskeleton, cell polarity, smooth muscle contraction, and multiple cellular functions. It controls stress fibers, focal adhesion formation, neurite retraction, and cell motility by phosphorylating substrates such as DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1, and PPP1R12A. ROCK1 Protein, Human (Sf9, His) is the recombinant human-derived ROCK1 protein, expressed by Sf9 insect cells , with N-8*His labeled tag. The total length of ROCK1 Protein, Human (Sf9, His) is 410 a.a., .

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